Edema symptoms after taking dexamethasone may be dexamethasone adverse drug reactions, should be targeted to change the treatment program or the use of medication and other treatments. The use of dexamethasone may cause endocrine disorders in the human body and the emergence of electrolyte disorders and other adverse reactions, specifically may be manifested in edema, menstrual irregularities, hypokalemia. When edema occurs after taking dexamethasone, according to the severity of the adverse reaction should be given diuretic symptomatic treatment or adjust the drug treatment program and other measures, but it is not recommended to stop taking dexamethasone without authorization. When edema occurs after taking dexamethasone, patients are advised to go to the Department of Rheumatology and Immunology of regular hospitals for detailed consultation in a timely manner and follow the doctor’s instructions for diagnosis and treatment.