Regardless of whether the liver cancer is in early, intermediate or advanced stages, antiviral treatment is required as long as hepatitis B virus infection exists. Since liver cancer often requires various treatments, which may include surgery, interventional therapy, radiotherapy, chemotherapy, etc. These treatments may increase the burden on the liver and aggravate the condition of hepatitis B. Therefore, antiviral treatment is needed first. These treatments may aggravate the burden on the liver and worsen the condition of hepatitis B. Therefore, antiviral treatment is needed first. Currently, the commonly used drugs in clinic are oral antiviral drugs, such as entecavir, tenofovir, sofosbuvir, etc. Usually entecavir is used as the drug of choice for hepatitis B, and sofosbuvir can be chosen for hepatitis C, and so on. In advanced stage of liver cancer, it is necessary to go to the hospital in time to get a clear diagnosis and treatment plan, use drugs under the guidance of doctors and avoid self-medication.