Sigmoid colon cancer PT3N0MX indicates stage 2A, which is the meaning of intermediate stage of sigmoid colon cancer. In clinical practice, TNM is usually used for staging, where T stands for primary tumor, while T3 indicates that the tumor has invaded the plasma membrane layer. Secondly, N stands for lymph node metastasis, while N0 indicates that lymph node metastasis has not yet occurred. m refers to distant organ metastasis, and MX can mean uncertainty of whether distant organ metastasis has occurred. It can be seen that sigmoid colon cancer PT3N0MX means the disease has entered the middle stage and lymph node metastasis and distant metastasis have not yet occurred. At this stage, it is recommended to alleviate the condition through surgical resection according to the patient’s physical condition. Secondly, after surgery should not be taken lightly, should follow the medical advice, with chemotherapy to assist in the treatment, to reduce the rate of recurrence of the disease. Commonly used drugs include fluorouracil, calcium folinate, oxaliplatin and so on. In the middle stage of sigmoid colon cancer, there may be symptoms such as increased frequency of bowel movements, blood in feces, abdominal pain and so on. Therefore, if long-term abdominal discomfort exists, attention should be paid to it and go to the hospital for examination as soon as possible.