Stomach pain with nausea, vomiting and acid reflux may be caused by gastritis, gastric ulcer, gastric cancer, reflux esophagitis, etc. Acid suppressants, mucosal protectants and gastrointestinal power drugs can be taken. 1. Acid inhibitors: acid inhibitors include proton pump inhibitors and histamine H2 receptor antagonists, the former including omeprazole and other drugs, the latter including famotidine and other drugs, which can inhibit gastric acid and improve the symptoms of stomach pain and acid reflux. 2. Gastric mucosal protective agents: Mucosal protective agents include gefalate tablets, Rebapatide tablets, magnesium aluminum carbonate chewable tablets, bismuth potassium citrate and other drugs, which can protect the gastric mucosa, enhance the gastric mucosal barrier, and improve the patient’s symptoms of gastroparesis and so on. 3. Promote gastric power medicine: Promote gastrointestinal power agent commonly used domperidone tablets, mosapride tablets, etc., can promote gastrointestinal peristalsis, thereby improving the patient’s nausea and vomiting, as well as acid reflux and other symptoms. The above drugs should be taken under the guidance of a doctor, and for women of childbearing age, it is also necessary to rule out whether the nausea and vomiting is caused by pregnancy, and at this time, it is necessary to avoid the use of drugs that will have an impact on the fetus. If the patient’s symptoms do not improve after taking the above medications, it is necessary to go to the hospital in time for further examination to determine the cause of the disease and follow the doctor’s instructions for treatment.