The lack of energy when the blood and urine tests are fine may be due to poor rest, which can be relieved after sufficient rest; if it continues to be unrelieved, we need to consider other systemic problems, such as digestive system (liver function abnormalities, etc.), urinary system (renal function abnormalities, etc.), endocrine system (diabetes mellitus, hypothyroidism, etc.), and psychological problems (depression, etc.), which all require timely hospitalization. 1. Poor rest: When work and rest are irregular or life and work stress are high, it will lead to poor rest and a feeling of lack of energy, which can be relieved by adjusting work and rest and getting enough rest. 2. Digestive system: When liver function is abnormal (such as hepatitis, etc.), it will cause lack of energy. Liver function, abdominal ultrasound and other related tests can help clarify the diagnosis. 3. Urinary system: when there are abnormalities in renal function (such as nephritis, renal failure, etc.), it will cause a lack of energy, and renal function, urinary ultrasound and other related tests can help clarify the diagnosis. 4. Endocrine system: when suffering from diabetes, hypothyroidism and other diseases, there will be a lack of energy, biochemistry, thyroid function, glycated hemoglobin and other related tests can assist in clear diagnosis. 5. Psychological problems: psychological problems such as depression, will make people feel weak, need to consult the hospital in time, depression assessment scale and other related tests can assist in a clear diagnosis. Blood and urine tests are not a problem, but the lack of energy, if there is no relief after sufficient rest, it is recommended to seek early medical attention, a clear diagnosis, to avoid delays in the condition.