The treatment of chronic renal failure is mainly to correct acidosis, correct water and electrolyte disorders, control hypertension, correct anemia, correct dyslipidemia and other treatments to slow down the progress of chronic renal failure. 1.Correcting acidosis: the main drugs for correcting metabolic acidosis, such as sodium bicarbonate, can often be basically corrected. For patients with obvious heart failure, prevent overdose, so as not to aggravate the burden on the heart. 2. Correct hydroelectrolyte disorders: sodium intake should be appropriately limited to prevent sodium retention, diuretics such as furosemide, hydrochlorothiazide and other diuretic and decongestive treatments can be used, and ion levels should be checked regularly. 3. Control hypertension: The control of hypertension is not only to control the symptoms, but also to protect the target organs such as heart, kidney and brain. 4. Correct anemia: we can consider applying recombinant human erythropoietin, iron polysaccharide, roxarestat and other treatments, usually applied when hemoglobin <100g/L, which can maintain hemoglobin around 110~120g/L. 5. Correcting dyslipidemia: statins such as atorvastatin and resuvastatin can often be applied to reduce blood lipids. If the disease progresses to uremia, renal replacement therapy is feasible. The above medications should be used in accordance with medical advice and standardized under the guidance of a physician. Patients with chronic renal failure are advised to consult regular hospitals for standardized treatment under the guidance of physicians.