The seriousness of diabetes: it is not in the diabetes itself but in its complications. Vascular lesions due to diabetes are the basis for the formation of complications. Diabetic foot and difficult-to-heal skin soft tissue wounds after diabetes, as a serious complication of diabetes, have a high disability rate. Due to vascular sclerosis, plaque formation, and nerve damage at the extremities of diabetic patients, blood vessels are easily occluded, and the “foot” is the farthest from the heart, where occlusion is most severe, leading to edema, blackening, decay, and necrosis, resulting in gangrene and eventual amputation. Diabetic patients account for 40-60% of all non-traumatic low limb amputations. Eighty-five percent of diabetes-related low distal amputations occur after foot ulcers. However, diabetic patients are mostly older, amputations are traumatic, wounds are difficult to heal, infections and recurrences occur easily, and mortality rates are as high as 51% within two years after amputation, while the rate of amputation of the contralateral limb is greater than 50%. Therefore, the treatment risk of diabetes with skin soft tissue injury is very high, and many patients who have this disease easily lose their confidence in life. Also, on average, 4 out of 5 ulcers in diabetic patients are induced or worsened because of trauma. Although many diabetic patients do not show obvious symptoms of lower limb ulcers, they are prone to various traumatic injuries (such as burns, scratching and breaking, mosquito bites, etc.) in their daily lives that cause skin defects in the lower limbs, which do not heal for a long time and are highly susceptible to infection and eventually lead to limb necrosis. In the past, these cases did not attract enough attention from doctors. Patients with chronic trauma were mostly scattered in departments such as endocrinology, general surgery, orthopedics, high-density wards and drug exchange clinics, where the treatment of primary diseases and chronic diseases was the main focus. The pain and helplessness are overwhelming. The current status of treatment for chronic small wounds in China is that many patients do not receive systematic, professional and standardized treatment. Such delayed treatment can easily lead to the expansion and deepening of small wounds, which become more difficult to heal and even form serious infections and aggravate the deterioration of the primary chronic disease. Therefore, active control of blood glucose levels, enhanced skin care of the lower extremities, early detection and treatment after the appearance of skin defects, and selection of the best individualized treatment plan are necessary to reduce the pain and shorten the course of the disease to achieve the best prognosis.