Closed mouths, also known as pimples, are classified as acne, along with pimples. It can be treated by general treatment, medication, laser surgery and other methods. 1. General treatment: Pay attention to cleanliness, and wash your face with mild cleansing products to minimize the oil adhering to the face and clogging the pores. At the same time, minimize the consumption of spicy and stimulating foods, reduce late night, and develop good habits. 2. Medication: Topical Vitamin A cream, azelaic acid and other medications can be applied to the affected area to remove keratin plugs, thus treating acne. 3. Laser surgery: Laser surgery can penetrate the skin and stimulate tissue renewal to treat acne. When acne is present, scratching and pressure should be avoided to avoid inflammation. When acne expands or does not improve significantly, patients can go to the hospital for professional treatment and should not use medication without authorization.