Sore throat and cough with phlegm may be caused by upper respiratory tract infection, reflux pharyngitis and other diseases, can be prescribed oral antiviral, cough phlegm, anti-infective, acid suppression drugs treatment. 1. Upper respiratory tract infection: As the upper respiratory tract is infected by germs, it is easy to cause sore throat and cough with phlegm. Antiviral treatment such as oseltamivir and famciclovir can be taken. At the same time, you can take cough suppressants such as dextromethorphan, codeine, etc. and expectorants such as acetylcysteine, aminoglutethimide hydrochloride. Acetaminophen and ibuprofen can be taken for severe sore throat. 2. Reflux laryngitis: Due to the reflux stimulation of gastric contents, the corrosion caused by the mucous membrane of the throat may cause sore throat and irritating cough with phlegm symptoms. Acid-suppressing drugs can be taken, such as omeprazole, cimetidine, etc. and the promotion of gastrointestinal dynamics drugs, such as mosapride, domperidone, etc.. When the patient has a sore throat and cough with phlegm, it is recommended to go to the hospital to identify the cause of the disease and then follow the doctor’s instructions to standardize the use of drugs and treatment.