Glucosamine hydrochloride tablets have some side effects, the common side effects are the following: 1. gastrointestinal reactions, such as mild nausea, vomiting, constipation or diarrhea, so it is recommended to take them with or after meals. 2. allergic reactions, which may cause skin allergies, itching and other symptoms. 3. there will be some effect on liver and kidney function, but the effect is relatively mild. Glucosamine hydrochloride tablets are drugs used for osteoarthritis and osteoarticular cartilage damage. This drug works slowly, and the overall side effects are not great and can be used for a long time. However, the dosage should be well controlled, and gastrointestinal reactions can easily occur if used in excess.