The causes of restless sleep in newborns are mainly due to the following conditions. First, it is caused by the newborn not having enough milk. The newborn’s gastrointestinal peristalsis is relatively fast, resulting in a very high number of breastfeedings. It is more obvious when the mother does not have enough breastmilk, and it is necessary to increase the amount of breastfeeding for the newborn in time. If breastmilk is really not enough, formula milk should be used for complementary feeding. Secondly, it is caused by vitamin D deficiency rickets in newborns. Newborns grow and develop quickly, and if they don’t pay attention to calcium and vitamin D supplementation, it will cause vitamin D deficiency rickets. In this case, in addition to restless sleep, the newborn’s sweating is also very high, and it is necessary to give the newborn timely supplementation of vitamin D as well as calcium, and to regulate the treatment accordingly.