The spots on both sides of the cheeks may be liver spots, freckles, sun spots, zygomatic nevus with brown color, etc. The occurrence of this disease is related to heredity, pregnancy, sun exposure and sex hormone changes. 1. Liver spots: chloasma is also known as “liver spots”, the occurrence of this disease is related to factors such as heredity, pregnancy, sun exposure and changes in sex hormones, etc. The patients mostly show symmetrical distribution of pigmentation spots of different sizes and irregular shapes. 2. Freckles: the occurrence of freckles is mostly related to heredity, and the patients mostly show hyperpigmentation spots on the nose and cheeks after birth, and frequent sun exposure will lead to the gradual increase of freckles and deepening of their color. 3. Sunspot: Sunspot is an acute damage reaction caused by strong light irradiation of the skin, and patients mostly show hyperpigmentation spots after sun exposure. 4. Zygomatic brownish-blue nevus: the cause of the disease is still unclear, and it is thought that it may be related to heredity, and the patients manifested as the symmetrical distribution of greenish-brown and grayish-black spots of hyperpigmentation on zygomatic area, and the hyperpigmentation generally deepens with the growth of age. For patients with spots on both sides of the cheeks, it is recommended that they go to the dermatology department of a regular hospital for a consultation, and then be actively treated under the guidance of a doctor after the cause of the disease has been clarified.