Uremia is a common outcome of various chronic kidney diseases that continue to progress to the late stage, a clinical syndrome characterized by metabolite retention, imbalance of water, electrolyte and acid-base balance, and systemic symptoms. Diagnosis needs to refer to the history, renal function tests (glomerular filtration rate, blood creatinine, etc.) and related clinical manifestations. Renal ultrasound can see the shape, location and size of the kidneys, etc. Only renal ultrasound can not detect uremia. Renal ultrasound can play an auxiliary diagnostic role in uremia period, through the ultrasound can understand the size of the kidneys, distinguish between acute and chronic renal failure, with or without the combination of hydronephrosis and so on. Early diagnosis, active and effective treatment of primary diseases, avoiding and correcting risk factors that cause the progression and deterioration of renal function are the basis of uremia prevention and treatment, and the key to protecting renal function and delaying the progression of chronic kidney disease. Uremic patients should go to the hospital in time and receive standardized treatment under the guidance of professional physicians.