Among advanced patients, some of them cannot tolerate radiotherapy and chemotherapy due to liver, kidney, heart and other comorbidities, and TCM is the only option for these patients. TCM treatment can reduce symptoms, improve the quality of survival and prolong the survival period. Under the guidance of TCM theory, the principle of treatment is to distinguish the evil from the positive and the deficient from the real, and to dispatch the medicine according to the combination of local and overall viewpoints, combining evidence-based treatment with disease-specific treatment, and combining the support of the positive with the elimination of the evil. Chinese medicine attaches great importance to the protection of positive energy in the treatment of malignant tumors, especially for advanced age patients, if we use strong medicine to attack the evil, it will hurt the positive energy of human body and aggravate the disease. According to Chinese medicine, different age groups have different physiological conditions and qi and blood deficits, and their pathological reflections have different characteristics, therefore, the therapeutic use of drugs should also be different. The elderly have reduced vitality, qi and blood deficiencies, and suffer from deficiency, or mixed deficiency and reality, so it is appropriate to treat deficiency, and to be cautious in attacking evil when deficiency and reality are mixed, and to use lighter medicines.