Rheumatism usually refers to diseases of the rheumatic immune system, such as systemic lupus erythematosus, rheumatoid arthritis, etc.; physical examination, laboratory tests and imaging tests are usually needed to make a clear diagnosis. 1. Physical examination: Rheumatic immune system diseases can affect multiple systems and organs throughout the body, so physical examination of blood pressure, pulse, skin, muscles, joints, heart, etc. is usually performed. For example, whether there is edema in the lower limbs, whether there is arrhythmia in the heart, whether there is atrophy or pressure pain in the muscles, and so on. 2. Laboratory tests: There are many laboratory tests, including routine blood test, routine urine test, liver and kidney function, anti-autoantibody, human leukocyte antigen test, humoral immune function, blood sedimentation, C-reactive protein and so on. These tests can reflect the severity of the disease to a certain extent. 3. Imaging examination: Imaging examination mainly includes joint X-ray examination, CT examination, MRI, ultrasonography, angiography and so on. These items are more targeted and can clearly reflect the condition of local tissues and organs. Rheumatic immune system diseases can involve blood vessels, heart, kidneys and other organs in serious cases, so it is recommended that patients seek timely medical treatment and follow the doctor’s instructions for standardized diagnosis and treatment.