The treatment plan for systemic eczema includes immunosuppressants, licorice drugs, antihistamines, as follows: 1, immunosuppressants: including tretinoin, cyclosporine, methotrexate, etc., before the use of medication need to be clear whether the patient meets the indications, need to check the routine blood, urine, stool routine, liver and kidney function, ions, glucose, and orthopantomograms of the pelvis. 2, licorice drugs: can be static point compound glycyrrhetinic acid monoammonium S sodium chloride injection, or oral compound glycyrrhetinic acid tablets for treatment. Or oral compound glycyrrhizin tablets for treatment; 3, antihistamines: including levocetirizine hydrochloride capsules and olopatadine hydrochloride tablets.