Hepatitis B triple positive patients are mainly treated with antiviral drugs under the conditions of massive replication of hepatitis B virus and obvious abnormalities of liver condition. 1. Massive replication of hepatitis B virus: if the virus is not controlled timely after infection, it will replicate in large quantities in the body, causing obvious increase of viral content, aggravating the burden on the liver, and causing obvious abnormalities of liver function in serious cases, so antiviral drugs (entecavir) can be applied to control the disease. 2. Abnormal liver condition: when liver damage such as cirrhosis and obvious liver fibrosis are found during hepatitis B teratitis III, basically antiviral drugs need to be applied, and antiviral drugs such as entecavir need to be applied regularly. Hepatitis B triple sun patients themselves have a certain degree of contagiousness, please timely hospitalization and medical examination, diagnosis of the disease after standardized treatment, to avoid delays in the condition. At the same time, do a good job of daily protection to avoid cross-infection and transmission to others.