Sometimes hot and sometimes cold in the center of the feet may be due to deficiency of kidney yin and yang, but the exact cause should be decided by the doctor according to the patient’s other symptoms. Clinical symptoms of kidney yin and yang deficiency can be seen in the heart of the feet sometimes hot and sometimes cold, mental depression, fear of cold, dry mouth and throat, dizziness, tinnitus, lumbar and knee pain and weakness, loss of libido, impotence of men, spermatorrhea, spermatorrhea, infertility of women, with a clear and dilute, urination clear and long or residual leaching, or water stopping the skin and see edema, and so on. Kidney yin and yang deficiency patients, usually should pay attention to the combination of work and rest, avoid overwork, strengthen physical exercise, enhance physical fitness; according to the physical condition, can be appropriate for walking, qigong exercise and playing taijiquan and other activities. If the heart of the feet sometimes hot and sometimes cold symptoms for a long time without relief or accompanied by other discomfort, timely medical care, identify the causes, targeted treatment.