Interstitial nephritis and glomerulonephritis are two different kidney diseases with different disease characteristics, so you can’t compare which one is more serious and can’t make a generalization.
Acute glomerulonephritis is a self-limiting disease, and most of them have a better prognosis. However, acute interstitial nephritis is mostly caused by infections, medications and other factors, and the prognosis is also better when hormone therapy is given under the guidance of a doctor after eliminating the causative factors.
The prognosis of chronic interstitial nephritis varies a lot between patients, some patients can keep the disease state of chronic interstitial nephritis for a long time and the condition is more stable, but some patients progress faster and even develop into chronic renal failure sooner.
Chronic interstitial nephritis is caused by a variety of factors, with the development of the disease, and finally usually develop into renal failure, the prognosis is not good.
Interstitial nephritis as well as glomerulonephritis belong to different kinds of kidney diseases and it is impossible to compare which one is more serious. However, no matter which of the above mentioned diseases you are suffering from, you should take active treatment under the guidance of a nephrologist.