The common causes of the feeling of something blocking the throat include: acute pharyngitis, epiglottis cyst, hypopharyngeal cancer, reflux esophagitis and so on. 1. Acute pharyngitis: when the mucous membrane of pharynx is attacked by bacteria, viruses and other pathogens, inflammatory reaction will lead to congestion and edema of the mucous membrane, which will make the patient feel that there is something blocking the throat. 2. Epiglottis cysts: larger epiglottis cysts can cause compression of neighboring tissues and organs, which will lead to the symptom of something blocking the throat, or even the feeling of obstruction of swallowing, or even dyspnea. 3. Hypopharyngeal cancer: the most common type is squamous cell carcinoma of hypopharyngeal mucosa, with the growth and development of the cancer, it will cause patients to have the feeling of obstruction in the throat, foreign body sensation, feeling that there is something blocking the throat, and even difficulty in swallowing. 4. Reflux esophagitis: it is easy to make gastric reflux, which will stimulate the entrance of upper esophagus, and then there will be a sense of blockage in the throat, which will make the patient feel that there is something blocking the throat. If there is a feeling of something blocking the throat, it is recommended to actively go to the regular hospital, to clarify the cause of the disease and targeted treatment.