Renal nodules are different from renal tumors in terms of morphology, nature, and imaging manifestations. 1. Morphology: renal nodules are relatively regular, which can be manifested as round or round-like abnormal proliferative tissues in the kidney. On the other hand, renal tumors have a variety of morphology and are mostly irregular occupying lesions. 2. Nature: renal nodules are mostly benign, while renal tumors are mostly malignant, both of them need to be pathologically examined in order to correctly diagnose whether they are benign or malignant. 3. Imaging manifestation: renal nodules are abnormal protrusion of kidney part, thus forming nodular changes, which are closely connected with kidneys. On the other hand, renal tumors can grow in various places, such as inside the kidney, outside the kidney, or on the surface of the kidney, which are less closely related to the kidney. When kidney nodules or kidney tumors are suspected, you should consult a doctor in time for diagnosis and treatment by a professional doctor.