Mixed thyroid nodules need to be treated according to the severity of the condition, and surgery is required if the nodules are malignant. Mixed thyroid nodules are nodules that are partly cystic and partly solid. The cause of the nodules may be follicular adenomas, adenomatous nodules, etc., which need to be considered according to the patient’s thyroid function and nodule classification. If the nodules are functional and hyperthyroidism is present, surgical treatment is needed. If the nodules have malignant signs such as irregular margins, tiny calcifications, and aspect ratio disorder, further fine needle aspiration biopsy of the thyroid is needed, and if the nodules are malignant, surgical treatment is needed. Patients with mixed thyroid nodules should be examined and treated under the guidance of specialized doctors.