Suddenly waking up at night and feeling a sense of panic in the heart may be phytoneurosis, cardiovascular disease (such as arrhythmia, etc.), endocrine system diseases (such as hyperthyroidism, etc.), need to be specifically analyzed. 1. Phytoneuropathy: it is a kind of autonomic nervous function disorder, and long-term mental stress, mental tension, age, gender and genetic factors, clinical symptoms can involve all systems, can be manifested as palpitations, chest tightness, etc., can be improved by taking nutritive drugs (such as ghrelin) and relieving stress, such as not relieved or continue to aggravate, it is recommended to seek early medical attention. 2. Cardiovascular diseases: such as various types of arrhythmia, coronary heart disease, hypertension, etc., there may be a sudden discomfort of the heart and wake up at night with palpitations and panic, etc. Electrocardiogram, coronary CTA (CT angiography), and blood pressure monitoring can assist in the diagnosis. 3. Endocrine system diseases: Hyperthyroidism may cause palpitation and chest tightness due to accelerated metabolism, increased cardiac load and tachycardia, which is more obvious at night; while diabetes mellitus may cause nocturnal awakening with palpitation and weakness due to poor glycemic control and hypoglycemia at night. Thyroid function and glucose tolerance test can assist in making a clear diagnosis. It is recommended to go to the hospital as soon as possible to get a clear diagnosis and timely treatment to avoid delaying the condition.