Itchy foot seams may be caused by tinea pedis, eczema or palmoplantar pustulosis. 1. Tinea pedis: a superficial fungal infectious disease that occurs in the skin of the feet between the toes and the metatarsals of the feet, blisters or macerated vesicles can be formed at the foot crevice, at this time the affected area is obviously itchy, and the vesicles can be gradually exposed. 2. Eczema: If acute eczema occurs, the hands, feet, face and other places can be first manifested as erythema-based papules, papules, consciously have intense itching, severe papules into blisters, vesicles can be formed. 3. Palmoplantar pustulosis: the lesions are blisters at the beginning, gradually become pustules, pustules become dry and crusty, scaly, often occurring in the center of the soles of the feet or palms of the hands, gradually spreading to the soles of the feet or the rest of the foot, the affected area has a variable degree of itching. It is recommended that when itching and skin lesions appear on the toe crevice, consult the hospital in time and follow the doctor’s instructions for treatment, and pay attention to keep the feet clean and dry.