High HDL is a protective factor against coronary atherosclerosis and is a good sign, but too high is possibly related to liver damage. HDL is due to cholesterol synthesized by the liver, and its main physiological function is to transport phospholipids and cholesterol, which can play an anti-atherosclerotic role, and is a protective factor for coronary atherosclerotic heart disease. However, high HDL cholesterol values can also be harmful to the body, most commonly seen in cholestatic cirrhosis, chronic hepatitis, and alcoholic liver injury. Taking niacin drugs may also cause high HDL levels. If you have high HDL cholesterol levels, it is recommended that you consult the cardiovascular medicine department of a regular hospital.