Nine-valent vaccine is not recommended over 26 years of age, and quadrivalent vaccine can be given over 26 years of age. The nine-valent vaccine protects against nine subtypes of infection, such as HPV 16, 18, 6, 11, 31, 33, 45, 52, and 58. However, it is clearly stated that it can be given to women between the ages of 16 and 26. If the injection is given beyond the age of 26, its preventive ability may be reduced. Therefore, it is not recommended that women over 26 years of age receive the nine-valent vaccine. However, women over the age of 26 who are younger than 45 can get the quadrivalent vaccine. The quadrivalent vaccine protects against the four types of HPV 16, 18, 6 and 11. The entire vaccination process requires three shots of this kind, with a two-month interval between the first and second vaccinations, and a four-month interval between the second and third vaccinations. Both the nine-valent vaccine and the quadrivalent vaccine have a certain preventive effect on HPV, and you can choose the vaccine that suits you under the guidance of your doctor and in conjunction with your own situation.