Patients with advanced gastric cancer have a poor prognosis, and their survival time is mostly judged by five-year survival rate, which is about 10%. Patients with advanced gastric cancer mainly suffer from upper abdominal pain, which is progressively aggravated, accompanied by symptoms such as vomiting blood and black stool, and most of them will show weight loss. Most patients with advanced gastric cancer are not suitable for surgery and can be transferred to medical oncology for follow-up treatment such as radiotherapy. Patients with advanced gastric cancer are often unable to eat and lose appetite due to pain, so they need to be treated with gastric tube or enteral nutrition support. Ensuring normal nutrition supply has a more important impact on the survival of patients with advanced gastric cancer. For patients with advanced gastric cancer, it is necessary to weigh the pros and cons, and the priority principle is to reduce patients’ pain, and not to choose surgery blindly. In addition, patients with advanced gastric cancer need to actively adjust their mentality, quit smoking and drinking, eat less and more meals, strengthen nutrition, eat reasonably, and live a healthy lifestyle that will help them live longer.