Hormones: Hormones are often referred to as short for adrenocorticotropic hormones: common ones are prednisone, dexamethasone, cortisone, and so on. These drugs will reduce mucus secretion and promote gastric acid and pepsin secretion. Patients with hyperacidic gastritis and peptic ulcer will be aggravated by the use of these drugs, and in severe cases, gastric perforation and bleeding can occur. Therefore, patients who need to take such drugs for a long time need to be taken orally with acid inhibiting drugs, commonly used drugs that inhibit gastric acid include proton pump inhibitors, such as so-and-so razole. Generally speaking, in the acute and active stage of gastric disease, the above drugs are prohibited. If you have to use the above drugs in the stable and remission period of gastric disease, it is recommended to take the drugs after meals to reduce the direct contact between the drugs and the gastric mucosa during fasting, which may cause damage to the stomach. You can also take microfilm protectants such as aluminum sulfate before taking the drug. Non-steroidal anti-inflammatory drugs: Non-steroidal anti-inflammatory drugs are most commonly painkillers, including aspirin, indomethacin, ibuprofen, naproxen, diclofenac and so on. These drugs are widely used, from small fever and cold, headache, toothache and other common diseases, to the treatment of osteoarthropathy, rheumatoid arthritis and the prevention of cardiovascular and cerebrovascular complications. Especially middle-aged and elderly patients, long-term oral small-dose aspirin enteric-coated tablets, a meal is half a year or even a few years, the gastrointestinal stimulation of the slight gradual accumulation of gastric and intestinal, easy to cause acute gastric mucosal lesions, erosive hemorrhagic gastritis, peptic ulcer bleeding and so on. It should be noted that most cold and flu medicines contain these antipyretic and analgesic drugs that may injure the stomach. There are also some drugs that can produce gastric irritation to the stomach to produce gastrointestinal discomfort symptoms, such as antibiotics, potassium chloride, some hypoglycemic drugs, etc., generally rarely cause gastrointestinal bleeding. It is recommended that if you are taking hormonal drugs and non-steroidal anti-inflammatory drugs, indigestion, acid reflux, abdominal pain, bloating and other symptoms should be taken seriously, and if necessary, gastroscopy to clarify the cause of the disease. Try to take drugs within half an hour after meals to reduce the stimulation and damage of drugs to the gastric mucosa.