Anal plug pain relief suppository is a kind of non-steroidal anti-inflammatory drug, which has a very good pain relief effect. However, it also has certain side effects, including the following: 1, if the dose of this kind of drug is too much, the patient will have hypothermia, sweat discharge is too large phenomenon, which will lead to the emergence of defecation, and even serious cases of hemorrhagic shock and metabolic acidosis. 2, there are certain side effects on the gastrointestinal tract, the use of which will cause nausea, vomiting and drug-induced ulcers. Drug ulcers occur, when the situation is serious, black stools and vomiting blood symptoms. 3, if the patient suffers from coronary heart disease, in the use of pain suppositories must be moderate, but also to closely observe the patient’s heart condition, because this drug is very easy to induce the occurrence of coronary heart disease.