Reduced liver size can be the advanced stage of portal cirrhosis, which can also be seen in acute and subacute severe hepatitis, and the condition is extremely serious. 1. Advanced stage of portal cirrhosis: Early cirrhosis has mild symptoms, such as loss of appetite, dyspepsia, abdominal distension, nausea, fatigue, dizziness and emaciation, etc. The above symptoms are aggravated in advanced cirrhosis. In advanced cirrhosis, the above symptoms are aggravated, and there may be edema, abdominal fluid accumulation, jaundice, skin and mucous membrane bleeding, fever, hepatic encephalopathy, oliguria, anuria and other symptoms, and the condition is critical. 2. Acute and subacute severe hepatitis: a series of manifestations of liver failure, such as hepatorenal syndrome, hepatic encephalopathy, etc., can occur in severe hepatitis, and the condition is more serious. (1) Early stage of acute severe hepatitis can have no obvious shrinkage of liver, about 1 week later, the liver is extensively necrotic, and the necrotic area can be up to 2/3, at this time, the volume of liver is obviously reduced, and the rate of death is higher, and the course of the disease is usually 3 weeks. (2) In subacute severe hepatitis, the area of hepatic necrosis can be up to 1/2, the volume of the liver is obviously reduced, the surface can be nodular, the duration of the disease can be more than 3 weeks, and the prognosis is very poor. The condition and prognosis of patients with reduced liver volume should consult a professional physician for comprehensive judgment and actively cooperate with the treatment.