Possible causes of severe hair loss include resting alopecia, androgenetic alopecia, pemphigus, ringworm, etc., which can be treated with the help of topical medications and oral medications. 1. Resting alopecia: when the patient has a long stay up late, lack of sleep, mental stress, etc., may make the hair follicle growth cycle regulation changes, causing hair loss symptoms. This kind of patients should pay attention to strengthen the adjustment of lifestyle, to ensure sufficient sleep and good state of mind, diet to light diet, strengthen nutrition, etc., so as to help alleviate hair loss. 2. Androgenetic alopecia: Androgenetic alopecia is a common cause of hair loss in clinic, which will cause a series of manifestations such as miniaturization of scalp hair follicles, reduction of hair, receding hairline and baldness. This kind of patients can take oral finasteride, cyclopropylprogesterone and other drugs to regulate the level of androgen in the body, and topical application of minoxidil and other methods to help treat hair loss. 3. Patchy baldness: the typical performance of patients with patchy baldness is the sudden appearance of clear patches of hair loss on the scalp, such patients can help improve hair loss by topical or local injection of glucocorticoids, applying minoxidil, taking cystine, calcium pantothenate, vitamin B and other medications, and in severe cases, hair transplantation can be considered. 4. Tinea capitis: Scalp area infected by various fungi may cause tinea capitis, causing itching, hair loss and other symptoms. This kind of patients can apply local bifonazole cream, terbinafine cream and other ointments, and in serious cases, oral itrazolecon, terbinafine and other drugs can be taken on this basis to help improve hair loss. It should be noted that the above treatments need to be carried out under the guidance of a physician. Avoid self-medication.