After taking medication, after the major triple positive has turned into minor bi-positive, you can go to the hospital for virus test and liver function test, if both of them are no different then no treatment is needed, otherwise treatment is needed. Major triple positive means that hepatitis B patients have many viruses in their bodies, which replicate quickly and are highly infectious, while minor bi-positive indicates that hepatitis B patients have reduced replication ability. However, the clinical significance of transforming from triple positive to minor bi-positive is not great. It mainly depends on whether the virus has mutated and whether the liver is damaged. You can go to the hospital for virus testing to see if the mutated virus caused the change from major triple positive to minor triple positive, if so, treatment is needed, if not, you should go to test the state of the liver, if the liver function is damaged, treatment is also needed, if the liver function is not damaged, it means the disease is getting better and no treatment is needed. Hepatitis B can be treated with interferon or nucleoside analogs or antiviral blocking drugs under the guidance of a doctor, and early diagnosis and treatment to avoid further development of the disease is the right thing to do.