Sleeping during the day and not being able to sleep at night is due to the occurrence of sleep rhythm disorders, medically known as sleep inversions. There are two possible causes: 1) because the patient stays up late for a long time leading to sleep inversion; 2) pathological changes in the brain may occur, leading to rhythm disorders. It is recommended to visit the neurology department to improve the cranial magnetic resonance examination to rule out any organic brain disease. If there is no abnormality, oral sleep regulating drugs can be taken to correct the circadian rhythm. Drugs that regulate melatonin secretion are currently recommended, as well as drugs that enhance melatonin receptor sensitivity, such as agomelatine and trazodone. If there are clear external factors intervening such as the inability to sleep at night on night shifts, patients are advised to try to adjust their work to improve their sleep rhythm, otherwise it will have adverse effects on the body in the long run.