Swelling and pain are associated with local soft tissue infections, and local soft tissue injury following trauma can also manifest as edema and pain. If necessary, further cold compresses are needed to relieve symptoms and inhibit local hematoma expansion. In case of co-infection, intravenous anti-infection therapy is also required. There are also patients who suffer from poor venous blood return, and the corresponding area may show significant swelling, pain, increased skin temperature or even fever, such as venous thrombosis of the lower extremities. A clear diagnosis should be actively treated with anticoagulation to improve microcirculation obvious swelling and also elevate the limb to reduce the discomfort in the distal limb by gravity. If necessary, the application of elastic bandages can also be chosen to reduce the patient’s discomfort.