How long can radiofrequency ablation of liver cancer last can not be determined in general, it is mostly related to individual’s condition, the 5-year survival rate of early-stage liver cancer can reach more than 70%, while the 5-year survival rate of late-stage liver cancer is relatively low. Radiofrequency ablation is mainly used to implant radiofrequency ablation needles into tumor tissues under ultrasound guidance, so as to cause necrosis of tumor tissues, which is less traumatic, quicker recovery, and with precise curative effect. It is mostly used for patients with small liver cancer in early stage. The 5-year survival rate of liver cancer treated with radiofrequency ablation in early stage of liver cancer can reach more than 70%, while the 5-year survival rate of liver cancer treated with radiofrequency ablation in advanced stage of liver cancer is relatively low. Review and evaluation can be done 3-6 weeks after the first treatment. If the result is satisfactory but there are still symptoms or imaging and other tests suggest that the lesion still exists, a second treatment may be needed, mostly after 2 months of the first treatment. However, too many treatments may cause liver cell necrosis and may even lead to liver failure. It is recommended to determine whether radiofrequency ablation for liver cancer is needed according to individual’s situation under doctor’s guidance.