After the diagnosis of otolithosis is confirmed, comprehensive treatment is usually needed, such as manipulation or machine repositioning and medication for symptomatic treatment, and medication is only auxiliary to relieve the symptoms, such as the application of methylcobalamin, betahistine, and flunarizine. 1. If mild otolithiasis is not found to be positive in the postural test, but there is occasional vertigo, and the number of times gradually decreases, some medications, such as methylcobalamin, betahistine, etc., can be taken as an aid. 2. If the vertigo is severe, accompanied by nausea and vomiting, we need to apply isopromethazine hydrochloride, betahistine and other anti-dizziness treatments, and choose the route of medication as appropriate; after the vomiting and other discomforts are relieved, we need to carry out postural test to clarify the location of otoliths in the semicircular canals and the position of otoliths in the semicircular canals, so that we can use manipulation reset or machine reset to treat the otoliths, and after that we can take methylcobalamin, betahistine, flunarizine, and other symptomatic treatments. In conclusion, if otolithosis occurs, it is recommended to consult a regular hospital in time and follow the doctor’s instructions for standardized treatment.