The four drugs used in the treatment of heart failure are generally angiotensin-converting enzyme inhibitors/angiotensin receptor enkephalinase inhibitors (ACEI/ARNI), beta-blockers°, aldosterone receptor antagonists, and sodium-glucose cotransporter protein 2 inhibitors. ACEI/ARNI, including captopril and enalapril, such drugs improve myocardial remodeling and are helpful in the long-term prognosis of heart failure. Beta-blockers, such as bisoprolol and carvedilol, which lower heart rate and reduce myocardial oxygen consumption. Aldosterone receptor antagonists, such as aldosterone, reduce the body’s blood volume and lessen the heart’s workload. Sodium-glucose cotransporter protein 2 inhibitors, including empagliflozin and dagliflozin, can reduce the risk of death and hospitalization in patients. When a patient develops heart failure, he or she should go to the hospital promptly and be treated aggressively under medical supervision.