Metformin extended-release tablets can have one in the morning and two in the evening, but the specific is not good need to be combined with the actual situation to decide, metformin extended-release tablets have different specifications and the specific dosage varies from person to person, please follow the doctor’s instructions to take. Metformin extended-release tablets can inhibit hepatic glucose production, reduce intestinal absorption of glucose, increase peripheral glucose uptake and utilization, and then play the purpose of lowering blood glucose; can be used for the treatment of type 2 diabetes mellitus relying solely on physical exercise and dietary control of blood glucose is ineffective. Allergic to this drug, severe renal failure, acute metabolic acidosis, hepatic insufficiency is prohibited. Metformin extended-release tablets have different specifications, the specific dosage varies from person to person, please follow the doctor’s instructions. Metformin Extended-Release Tablets 500mg size, the starting dosage is usually 500mg once a day with dinner. The dosage is adjusted according to blood glucose and urine glucose, and the maximum daily dose does not exceed 2000mg. If 2000mg once daily does not achieve satisfactory efficacy, it can be changed to 1000mg twice daily. Adverse reactions such as nausea, hypoglycemia, abdominal distension, abdominal pain, lack of appetite, dizziness, headache, palpitations, hot flashes, abnormalities of hepatic function, and urticaria may occur after administration. Patients requiring treatment with Metformin Extended-Release Tablets should use the medication under the supervision of a doctor.