Symptoms of systemic poisoning are mainly manifested as dysfunction of various systems of the body, for example, dysfunction of the digestive system will appear nausea, vomiting, abdominal pain, diarrhea and so on. The respiratory system is mainly characterized by irritating cough, laryngeal edema, or even dyspnea and cyanosis caused by pulmonary edema. If it affects the central nervous system, dizziness, headache, nausea, vomiting, poor mental concentration will occur in mild cases; in severe cases, there will be blurring of consciousness, irritability or even coma, convulsions, shock and so on; the most serious cases will lead to central respiratory failure, respiratory arrest and death. Liver and kidney functions will be affected, such as jaundice, oliguria or anuria, generalized sunken edema and so on.