Decubitus ulcers are ulcers formed by continuous pressure on local tissues and impaired blood circulation, resulting in ischemia, hypoxia, and malnutrition, causing tissue necrosis. It usually occurs at the site of tissue compression, especially at the site of the bone bulge. If not handled properly, a variety of complications can occur, such as cellulitis, abscess, osteomyelitis, sepsis, endocarditis, etc. Decubitus ulcers significantly prolong the hospital stay, increase hospital costs, and increase the death rate by 4 to 6 times. According to the literature, about 60,000 people die each year from bedsore complications. In the last 20 years, despite significant advances in the treatment and care of trauma, the incidence of decubitus ulcers and the overall outcome of treatment have not improved significantly. The first step in the treatment of more severe decubitus ulcers is to remove the necrotic tissue, which we refer to as debridement. In the treatment of decubitus ulcers, maggot debridement shows irreplaceable superiority. Jiang Kechun, Department of Endocrinology, Nanjing 454 Hospital, PLA To elaborate on the safety and effectiveness of maggot treatment in the treatment of decubitus ulcers, Sherman RA. selected 103 patients with a total of 145 pressure ulcers, of which 67 patients including 92 wounds could meet the conditions of this study. Patients were divided into maggot treatment and traditional method treatment groups; maggot treatment was performed by placing 5-8 maggots per square centimeter for 48 hours each time, twice a week, and covering the wound with saline gauze or 0.125% sodium hypochlorite gauze between maggot treatments; traditional treatment consisted of applying antibiotics, hydrocolloid dressings, chemical debridement factors, calcium alginate, growth factors, and several A combination of non-surgical methods, etc. Digital camera photography measures the length, width and area and circumference of the ulcer, and conclusions are determined by the amount of decaying tissue removed, changes in the size of the wound, and whether the wound is healing. Most of the patients were diabetic or paraplegic with spinal cord injury. 43 wounds were treated with maggots and 49 wounds were treated with conventional methods. The results showed that maggot debridement was faster and more complete than conventional debridement, although the maggot-treated group had larger trauma areas. Within 2 weeks of starting debridement, the maggot treatment group had a significant reduction of 3.7 cm2 of necrotic tissue area, while there was no significant difference in the reduction of necrotic tissue area in the conventional treatment group within the same time frame. Healthy granulation tissue growth was faster in the maggot treatment group (P=0.002). At 3 weeks of treatment, the area of necrotic tissue in the maggot-treated group was only 1/3 of that in the conventional treatment group, while the granulation tissue was twice as large. In less than 5 weeks, 80% of the wounds in the maggot treatment group were cleared, while 52% of the wounds in the conventional treatment group were still not completely cleared after 5.5 weeks (P=0.021). This study showed that the maggot treatment group was more effective and efficient in the treatment of decubitus ulcers compared to the current conventional treatment methods. The maggot treatment group was two to four times more effective than the conventional treatment group. Although the area of decubitus ulcers was larger in the maggot treatment group than in the conventional treatment group, the maggot treatment group reduced the area of decubitus ulcers twice as fast as the conventional group. Granulation tissue grew twice as fast as in the conventional group over an average treatment period of 5-6 weeks. The healing rate in the maggot treatment group was almost twice that of the conventional group, although 16% of the patients in the conventional group were those who did not want to receive maggot treatment because they thought their results with conventional treatment were ideal. The study did not compare maggot treatment with surgical debridement, which is a more effective debridement method than maggot removal, but maggot debridement was shown to be superior in some cases where surgical debridement could not be performed.