Folliculitis is a purulent inflammation confined to the mouth of the hair follicle, which is mainly related to Staphylococcus aureus infection. Buttock folliculitis can be treated with general treatment, topical medication, oral medication and so on. 1. General treatment: attention should be paid to skin cleanliness and hygiene, prevent trauma and enhance the body’s immunity. 2. Topical medication: patients can use iodophor solution for topical application, which will play the role of sterilization and disinfection. You can also apply fusidic acid, mupirocin and other anti-infective ointment, which can play an anti-infective effect. 3. Oral medication: If the patient’s buttock folliculitis infection symptoms are more serious, there has been a fever, proliferation and obvious swelling and pain phenomenon, you need to be under the guidance of a professional physician oral medication, to increase the therapeutic effect of the commonly used drugs, including clindamycin, amoxicillin and so on. It is recommended that patients with buttock folliculitis go to the hospital in a timely manner, under the guidance of the doctor to standardize the treatment. The medication should be used in accordance with the doctor’s instructions, do not self-medicate.