Taking estradiol after pregnancy may cause malformations in the fetus, the specifics vary from person to person, but it is not certain that it will cause malformations, it is just a possibility. The instructions for estradiol say that it is contraindicated in pregnancy and may cause malformations in the fetus, but the specifics vary from person to person and do not necessarily lead to malformations. Estradiol can also be used as needed when preserving the fetus, and can also be taken two months before embryo transfer pregnancy, but the medication should be used as prescribed. Taking estradiol for pregnancy is recommended to go to the hospital for timely consultation and examination, subject to the doctor’s guidance and recommendations, in order to prevent delays in the condition, resulting in other damages.