The clinical symptoms of bone metastasis from prostate cancer include the following. Patients may have severe and continuously increasing pain symptoms due to severe bone destruction, which includes osteolytic, osteogenic and mixed bone destruction, with osteolytic bone destruction being the most common. In addition, patients may also have pathological fracture, which can be caused by slight external force after the bone strength is changed, resulting in fracture deformity, abnormal movement, bone rubbing sensation and bone rubbing sound. If prostate cancer metastasizes to the spine and causes destruction of the vertebral body, compression fractures of the spine may occur, compressing the spinal cord nerves and causing motor sensory impairment of the lower extremities.