Prior to a psychotic episode, the vast majority of patients have had a period of nonspecific, nonpsychotic symptoms that are precursors to a decline in social functioning, such as social avoidance, poor social adjustment, decreased ability to perform daily tasks, and poor coping skills in life; and altered mental status, such as perceptual changes, implicated perceptions, delusional moods, and split-like personality. Psychotic episodes are associated not only with positive or negative symptoms, but also with syndromes with specific diagnoses. Studies have shown that patients present with negative symptoms earlier than positive symptoms. It is well documented that the period from the first onset of psychotic symptoms until the first treatment, called the duration of untreated psychosis (DUP), lasts approximately 1 to 2 years. The available neuropathological and brain mapping data on schizophrenia suggest that schizophrenia is a progressive developmental disorder. An important aspect of early treatment is that it interrupts the progression of the disease, including pathophysiological and biochemical processes that are not well understood at this time, thereby eliminating the conditions upon which the disease continues to progress. One of the effects of antipsychotic drugs is to reduce the reduction in the density of cells in the brain, especially in the basal ganglia, to the point of interfering with the pathophysiological processes of the disease and reducing decline. In terms of the effectiveness of treatment for schizophrenia, the more complete the treatment, the less likely it is that schizophrenia will develop in the future. The concept of “early stage” is defined in relation to the “general case”. “Early” means before the full onset of psychosis or when the DUP is very short. Intervening early in the onset of symptoms of schizophrenia, i.e., shortening the DUP, is done through the early use of medication or other treatments aimed at reducing the prevalence of the illness. Foreign studies found that patients with a DUP of 1 to 6 months had a significant reduction in the dose of all neural blockers in the acute and late acute phase; at one-year follow-up, hospitalization rates and length of stay were significantly lower, patient quality of life scale scores were significantly higher, and negative symptoms were significantly lower. Positive: implicated ideas, fragmentary delusions, strange speech. Negative: thinking/speech becomes less, emotions become indifferent, interest/socialization decreases. Personality: becomes introverted. Neuroticism: irritability, emotional instability, nervousness. Emotional: depressed mood. Social functioning: decreased social skills, decreased ability to learn/work. Early symptoms of Schizophrenia manifest: personality changes, neurotic-like disorder, sporadic incomprehensible behavior, paranoia, unreasonable preoccupation with a part of oneself. Intervention during the prodromal phase of schizophrenia Schizophrenia is a psychiatric disorder that young adults are vulnerable to. Its prognosis is poor, and the financial costs and emotional burden on the family are significant. In fact about 25% of patients with first onset have a poor prognosis. Recently, early detection and intervention in schizophrenia has been emphasized as a new and promising approach. There has been a large body of research discussing the concept of early intervention in schizophrenia. The prodromal symptoms generally have biological, psychological, and social alterations [], which manifest as decreased social functioning, such as social avoidance, poor social adjustment, decreased ability to perform daily tasks, and poor coping skills in life; and altered mental status, with changes in perception, implicated perceptions, delusional mood, and manifestations of a schizoid personality. During the period from January 2002 to June 2003, 17 cases, 9 males and 4 females, with an average age of 18±2.21 years and an average duration of illness of 7 months±3.23 months, were hospitalized in our early intervention ward and qualified for the diagnosis of prodromal schizophrenia. The education level was junior high school in 4 cases, high school in 5 cases, and university in 4 cases. All cases were evaluated jointly by two physicians with the title of deputy chief physician. The assessment was based on: personality changes, neuroticism, sporadic incomprehensible behavior, paranoia, unreasonable attention to a part of the body