What is the drug of choice for sleep-onset epilepsy

Sleep epilepsy is generally categorized as benign childhood epilepsy, autosomal dominant nocturnal frontal lobe epilepsy, and frontal lobe epilepsy. The drugs of choice are sodium valproate and topiramate for generalized epilepsy. They need to be chosen according to the type and characteristics of seizures as prescribed by the doctor, as follows: 1. benign epilepsy in children (BECT): most of them are partial seizures, benign epilepsy with central-temporal spikes or idiopathic pediatric benign occipital lobe epilepsy, which respond well to medications, and the preferred medications are carbamazepine, lamotrigine, valproate sodium or levetiracetam, which can be used singly with good efficacy. 2. Autosomal dominant nocturnal frontal lobe epilepsy: caused by genetic abnormalities, patients should use gene-specific enzyme-protein modulating drugs. The first choice of carbamazepine or lamotrigine can effectively control seizures, monotherapy is not effective, the need to use more than two drugs, you can consider adding clonazepam together. 3. Frontal lobe epilepsy: oxcarbazepine and carbamazepine are preferred. For refractory frontal lobe epilepsy, other antiepileptic drugs such as valproate and lamotrigine should be combined. For patients with seizures that are difficult to control, lamotrigine or topiramate can be chosen. If the use of carbamazepine and phenytoin sodium leads to deterioration of EEG, hormones can be used for treatment. Patients need to obey the doctor’s instruction and use the medication rationally. During the period of medication, regular testing of EEG and other indicators is important for the cure of the disease. In addition to cooperating with the medication, the patient’s correct rest and diet will help the recovery of the disease.