Endometrial cancer is not usually passed on directly to offspring, but there is a certain degree of familial aggregation of the disease. If there are patients with endometrial cancer in their parents’ generation, the chance of their offspring having the disease is relatively higher than that of the general population. The development of endometrial cancer is related to a number of factors, and can be caused by the long-term effects of endocrine factors, endometrial hyperplasia, exogenous estrogen stimulation, infertility, non-pregnancy, non-pregnancy, receiving long-term stimulation from radioactive factors, and heredity. A family history of the tumor exists in about 20% of patients with endometrial cancer. Endometrial cancer is not directly passed on to offspring, but may increase the chances of offspring developing the disease. People with a family history of endometrial cancer or with high risk factors for endometrial cancer are advised to undergo regular medical checkups, and if they experience discomfort such as irregular vaginal bleeding or lower abdominal pain, they should consult a doctor in time to clarify the cause of the disease under the guidance of a professional doctor and undergo active treatment.