Progesterone should not be taken if you are allergic to progesterone, have unexplained vaginal bleeding, thrombophlebitis, stroke, breast tumors or genital tumors. Progesterone is a progesterone drug, mainly used to treat dysfunction due to progesterone deficiency, irregular menstruation, dysmenorrhea and premenstrual syndrome, premenopausal disorders, etc., and has an important role in maintaining pregnancy. To use progesterone, you need to consult your doctor before using the drug. If you are allergic to progesterone or other components in progesterone, have unexplained vaginal bleeding, have vascular embolism, stroke, thrombophlebitis, or have a previous history of thrombophilia, have breast tumors or genital tumors, it is not suitable to use this drug. Progesterone should be used with caution if there are more serious underlying conditions, such as kidney disease, high blood pressure, heart disease, and unexplained edema.