Fusidic acid and metronidazole gel belong to two different drugs, so there is no which effect is better, according to the patient’s specific condition under the guidance of the doctor, choose the right drug for treatment. 1. Fusidic acid: it can be used for the treatment of various infections caused by various bacteria, especially staphylococcus, such as osteomyelitis, sepsis, endocarditis, recurrent infections of cystic fibrosis, pneumonia, traumatic infections and other diseases. During the use of fusidic acid ointment, some patients may experience localized skin adverse reactions, such as contact dermatitis, rash, eczema, erythema, itching, skin allergy and so on. For fusidic acid allergy patients are prohibited, fusidic acid ointment has an irritating effect on the conjunctiva of the eye, so avoid the use of around the eyes; such as the occurrence of serious irritation or allergic reaction, need to change to other drugs for treatment; fusidic acid can be absorbed through the placental barrier and can be secreted into the breast milk, so pregnant women and breastfeeding women should be careful with the use of. 2. Metronidazole gel: belongs to the anti-anaerobic drugs, can be used for inflammatory papules, pustules, rosacea erythema local treatment. In the process of use, local skin dryness, burning sensation and skin irritation and other allergic reactions can occur. In the process of use, be careful to avoid contact with the eyes and mucous membranes of the mouth and nose, if the site of the burning sensation and other abnormalities, you need to immediately stop the drug and wash clean; for the existence of allergies to the drug, pregnant women and breastfeeding women, as well as changes in the nature of the person, are prohibited from use. The use of specific drugs, need to be under the guidance of a professional doctor reasonable use, not self-medication.