HFMD is an acute infectious disease caused by a variety of enteroviruses, so theoretically HFMD can be cured, but the child may get HFMD a second or even a third time, because it is an infectious disease caused by a variety of enteroviruses. The main common viral types are enterovirus 71, coxsackievirus A16, and in recent years A6 and A10 are also common, as well as echovirus, so HFMD is not a lifelong immunity, and every HFMD can be eradicated and cured. However, if a child is infected with a different type of enterovirus, he may get HFMD for the second or even the third or fourth time, and we have seen some children who have been hospitalized twice or three times among the hospitalized patients. In principle, the key to eradicating hand, foot and mouth disease is to do a good job of personal hygiene and protection, in addition to exercise to improve their own immunity and resistance. One of the most effective prevention methods is vaccination against HFMD, but this vaccine is only for EV71, so it only prevents HFMD caused by EV71 virus infection.