Hiccups in the elderly may be the manifestation of chronic gastritis, gastric cancer and other diseases, or it may be the normal physiological reaction or adverse drug reaction. 1. Chronic gastritis: it refers to chronic inflammatory lesions of gastric mucosa caused by various etiological factors, usually related to Helicobacter pylori infection, autoimmune and other factors, with clinical manifestations such as vague pain in the upper abdomen, belching, acid reflux, and so on. 2. Gastric cancer: this disease belongs to malignant diseases of digestive tract, which is usually related to heredity, diet, Helicobacter pylori infection, etc. Early clinical manifestations include fullness and bloating, dyspepsia, loss of appetite, regurgitation of acid, belching and so on. 3. Normal physiological response: Normal diet is too full, too fast or excessive consumption of carbonated beverages, alcohol, etc., may make the diaphragm spasmodic contraction and hiccups. 4. Adverse drug reactions: the use of some drugs will affect the central nervous system, such as narcotics, steroids, sedatives and so on. Excessive use of these drugs will disrupt the body’s normal regulation of the nerve and related symptoms. If the symptoms of hiccups persist in the elderly, it is recommended to be vigilant and go to the hospital in time for a medical examination to clarify the cause.